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Fact Sheet: Obama Administration Announces New Manufacturing USA Institute, Third Institute Awarded in Three Weeks

December 21, 2016

The Advanced Regenerative Manufacturing Institute (ARMI), Inc., headquartered in Manchester, NH, brings nearly $300 million in public-private investment from leading manufacturers and universities to develop the cells, tissues, and organs that may one day restore form and function to wounded warriors and civilians.

Today, the Department of Defense is awarding the new Advanced Tissue Biofabrication Manufacturing USA institute, which brings together a consortium of 87 partners from across industry, academia, and government to develop the manufacturing technologies for life-saving cells, tissues, and organs. The winning coalition, led by ARMI, Inc. and headquartered in Manchester, NH will develop next-generation manufacturing techniques for repairing and replacing cells and tissues, which may one day lead to the ability to manufacture new skin for soldiers scarred from combat or develop organ-preserving technologies to benefit Americans waiting for an organ transplant.

The Advanced Regenerative Manufacturing Institute being announced today is the twelfth manufacturing hub awarded by the Obama Administration, and follows on the heels of two other hubs announced in the last two weeks—the National Institute for Innovation in Manufacturing Biopharmaceuticals, the first open-topic institute and the first institute awarded by the Department of Commerce, headquartered in Newark, DE; and the Rapid Advancement in Process Intensification Deployment Institute, awarded by the Department of Energy, headquartered in New York, NY.

Today at the White House, Under Secretary of Defense for Acquisition, Technology and Logistics Frank Kendall will announce the winning consortium before an audience of stakeholders from industry, academia, and government, including senior leaders from the White House, Department of Commerce, Department of Energy, and representatives from many of the existing Manufacturing USA institutes.

In the four years since its establishment, Manufacturing USA has grown from one institute with 65 members to a network of now 12 institutes with nearly 1,000 members. The institutes are already attracting new business investment to their regions, developing the cutting-edge technologies to drive American leadership, and training the workforce that will apply new skills to our manufacturing sector. Across the Manufacturing USA institutes, the Federal government has committed over $850 million, which has been matched by more than $1.8 billion in non-Federal investment. Today's progress builds on important bipartisan action from Congress, which in 2015 passed the bipartisan Revitalize American Manufacturing and Innovation to formally authorize the program, proving that strengthening American manufacturing is a goal on which we can all agree.

After a decade of decline from 2000 to 2009, the U.S. manufacturing sector has added over 800,000 jobs since early 2010. Despite recent headwinds, the foundation for U.S. manufacturing is stronger than it has been in decades. Just this year, a new report on global manufacturing competitiveness found that manufacturing executives view the United States as the best location in the world for manufacturing in the years ahead.

The New Manufacturing USA Institute Awards

Manufacturing USA connects people, ideas, and technology to solve industry-relevant advanced manufacturing challenges, enhancing industrial competitiveness and economic growth and strengthening our national security. Each manufacturing institute is designed to build U.S. leadership and regional excellence in critical emerging manufacturing technologies by bridging the gap between early research and product development; bringing together companies, universities, and other academic and training institutions, and Federal agencies to co-invest in key technology areas that can encourage investment and production in the United States while serving as a ‘teaching factory' for workers, small businesses, and entrepreneurs looking to develop new skills or prototype new products and processes.

Repairing and replacing cells, tissues, and organs. Announced today, the Advanced Regenerative Manufacturing Institute is poised to develop next-generation manufacturing techniques for repairing and replacing cells and tissues, which may one day lead to the ability to manufacture new skin for soldiers scarred from combat or develop organ-preserving technologies to benefit Americans stuck on organ transplant waiting lists. Headquartered in Manchester, NH, ARMI will focus on solving the cross-cutting manufacturing challenges that stand in the way of producing new synthetic tissues and organs—such as improving the availability, reproducibility, accessibility, and standardization of manufacturing materials, technologies, and processes to create tissue and organ products. ARMI will convene leaders from a multitude of disciplines, from cell biology and bioengineering to materials science and computer modeling. The partners will work to develop high-throughput culture and 3D biofabication techniques to non-invasive, real-time testing and sensing to measure the viability of engineered tissue constructs.

Industry Partners: Abbott, Autodesk, Becton Dickinson, Celularity, DEKA Research & Development, GenCure, Humacyte, Lonza, Medtronic, Rockwell Automation, and United Therapeutics

Government and non-profit organizations: FIRST, the State of New Hampshire, and Manufacturing Extension Partnerships in multiple states

Universities and Other Schools: Arizona State University, Boston University, Cedars-Sinai Medical Center, Dartmouth College, Harvard University, Massachusetts Institute of Technology, Rutgers, Stanford University, the University of Florida, the University of Minnesota, the University of New Hampshire, Worcester Polytechnic Institute, and Yale University

Life-saving bio-therapies. On December 16, Commerce Secretary Penny Pritzker announced the winner of the Department of Commerce's first institute and the first open-topic institute competition: the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL). NIIBML will be led by USA Bio Consortium, a team of more than 150 partners representing all of the elements required to make biopharmaceutical drugs—from the equipment makers and suppliers of raw materials, to the companies developing new treatments and readying them for clinical trials and regulatory approval, to the clinics treating patients. NIIMBL will work to accelerate the transition of disease-treating biopharmaceuticals from the lab to the market, with the aim to make these live-saving therapies more accessible to patients. NIIMBL will also help rapidly scale up manufacture of these advanced treatments to respond to pandemics and other biological threats, address drug shortages resulting from issues in manufacturing, and support precision medicine by exploring new processes and equipment to allow the cost-effective manufacture of single-batch biopharmaceutical exactly matched to an individual's genetics or disease. Read more here, and how NIIMBL's efforts will complement ARMI's efforts here.

Companies and Non-Profit Organizations: Agilent Technologies, AIChE, Air Liquide, Altimmune, Amgen, Amgen Foundation, Artemis Biosystems, Association of University Research Parks, ASTM, BioFactura, Biogen, BioHealth Innovation, Biologics Modular, BioPhorum Operations Group, bioVolutions, BMC Corp, Boehringer Ingelheim Fremont, California Manufacturing Technology Consulting, Celgene Corp, Charles River Laboratories, ChromaTan, Cimetrics, Colorado BioScience Association, Commissioning Agents, Inc, Connecting Connecticut's Science Community, Continuus Pharma, Corning Life Sciences, DelawareBio, DEMEP, DVIRC, Eli Lilly Research Labs, EMD Serono, FiberCell Systems, FloDesign Sonics, Fraunhofer CMB, Fraunhofer CESE, GBSI, GE Healthcare Life Sciences, Georgia Bio, Georgia Tech MEP, Grifols S.A., IBM, ILC Dover, ImmunoGen, Indiana Health Industry Forum, Institute for BioScience & Biotechnology Research, Intellia Therapeutics, IOWABio, Janssen Pharma, Juno Therapeutics, Kentucky Life Sciences Council, LakePharma, Lewa Process Technologies, Lonza Biologics Inc., Manex, MANTEC, MassBio, MassMep, MD MEP, MedImmune, MEPOL, MilliporeSigma, National Institute for Pharmaceutical Technology and Education, NC Bio, NC MEP, NEPIRC, NewYorkBIO, North Carolina Biotechnology Center, Novartis, Novo Nordisk, NYDSTI, Orochem, Pall Corp, Parental Drug Association, PBS Biotech, Pennsylvania Bio, Pfizer, Pharma Matrix, Pharyx Inc., Protein Sciences Corp, Purdue MEP, Regeneron Pharma, RepliGen, Rooster Bio, Sanofi Pasteur, SC MEP, Shire, Southwest Research Institute, SoyMeds, Stratosphere, Sudhin Biopharma, Tech Council of MD, Terumo BCT, THBI, Thrive Bioscience, University City Science Center, Unum Therapeutics, USP, Vericel Corp, Voyager Therapeutics, VWR, Waters

Universities, Colleges and Other Schools: Bio-Link (City College of San Francisco), Carnegie Mellon University, Clemson University, Delaware State University, Delaware Technical Community College, East Carolina University, Georgia Institute of Technology, Harvard University, IVY Tech Community College, Johns Hopkins University, MARBIONC: Marine Biotechnology in NC (UNC Wilmington), Massachusetts Institute of Technology, Memorial Sloan Kettering, MiraCosta College District, Montgomery College, Northeast Biomanufacturing Center and Collaborative, North Carolina Central University, North Carolina Community College's BioNetwork System, North Carolina State University, Pennsylvania State University, Purdue University, Quincy College, Rensselaer Polytechnic Institute, Solano Community College, The University of Texas at Austin, Tulane University, University of California Berkeley, University of Colorado Boulder, University of Connecticut, University of Delaware, University of Georgia, University of Iowa, University of Kansas, University of Kentucky, University of Maryland, University of Massachusetts, University of Minnesota, University of North Carolina Chapel Hill, University of North Carolina Charlotte, University of Pennsylvania, University of Wisconsin

State Government and Regional Organizations: Commonwealth of Pennsylvania, Massachusetts Life Sciences Center, State of Delaware, State of Maryland, State of Minnesota, State of North Carolina

States: Arizona, California, Colorado, Connecticut, Delaware, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maryland, Massachusetts, Minnesota, New Hampshire, New Jersey, New York, North Carolina, Pennsylvania, South Carolina, Texas, Washington, Washington D.C., Wisconsin

Ultra-efficient chemical manufacturing. On December 9, the Acting Assistant Secretary for Energy Efficiency and Renewable Energy in the Department of Energy David Friedman announced that the American Institute of Chemical Engineers will lead the Rapid Advancement in Process Intensification Deployment (RAPID) Institute. With over 130 partners from universities, companies, local and state organizations, and other Manufacturing USA institutes, the RAPID institute will work to develop new modular technologies to enable customized factories, local manufacturing in remote locations, and greater utilization of U.S. raw materials for manufacturing, while training future U.S. workers in these advanced fields. The RAPID institute will work to advance manufacturing processes used for making chemicals, refining fuels, and producing other everyday products used across the U.S. economy. By optimizing manufacturing at the molecular level, technologies developed by this institute will aim to save energy with every chemical reaction. In addition to improving energy efficiency, these technologies can lead to big savings on the manufacturing floor, such as cutting operating costs, waste, and equipment footprint. In the chemical industry alone, these technologies have the potential to save more than $9 billion in process costs annually. For example, by simplifying and shrinking the physical space needed for manufacturing, this approach may enable natural gas refining directly at the wellhead, saving up to half of the energy lost in the ethylene cracking process today. Read more here. Initial partners include:

Industry partners: Alloy Surfaces, Arkema, AspenTech, ATI Specialty Alloys, Automation Solutions, Avatar Sustainables, Ayers Group, BASF, BgtL, Biodico, Cantrell Capital, CB&I, Cermatec, CF Technologies, Compact Membrane Systems, Convergent Catalysis, Corning, Cummins, Domtar, Dow, Dow Water Solutions, DuPont, Earth Energy Renewables, Eastman Chemical, Easy Energy Systems, EcoCatalytic Technologies, Emerson Process Management, Enginuity Worldwide, Environmental & Fuel Research LLC, Environmental Engineering Solutions, ExxonMobil, Fluor, Franklin International, Full Cycle Bioplastics, FutureCeuticals, GE Water and Process Technologies, Greenway Energy, H Quest Vanguard, i3D MFG, Intellectual Assets, IntraMicron Inc., Italmatch Chemicals, Kore Infrastructure, Lubrizol, Managed Technology Solutions Group, Matric, NatureWorks, NuScale Power, Onboard Dynamics, Pall Corp., Paul Weaver Construction Equipment, Petron Scientech, Pioneer Tank & Vessel, Portland General Electric, Praxair, Process Systems Enterprise, Reliance Industries, RnD Consulting, Roeslein Alternative Energy, Saint Gobain NorPro, Secat Inc., Shell, Sigma Innova, Solar Fuels & Chemicals, Solvay, Southern Company, Strategic Analysis, United Technologies Research Center, Vacuum Process Engineering, vanZoen, Waste Resource Recovery, Xcel Energy, Zaiput Flow, Zeachem, Zeton

Local and State Organizations: Alabama Department of Commerce, Iowa Economic Development, Iowa Energy Center, State of Oregon, Oregon Manufacturing Extension Partnership, South Carolina Department of Commerce, South Carolina Manufacturing Extension Partnership

Academic Partners and Research Institutions: Auburn University, Carnegie Mellon University, Case Western University, Clemson University, Drexel University, Georgia Institute of Technology, Iowa State University, Manhattan College, Michigan State University, Massachusetts Institute of Technology, North Carolina State University, Oregon State University, Rutgers University, State University of New York, Texas A&M, Texas Tech University, University of Alabama, University of Arizona, University of California at Los Angeles, University of Delaware, University of Idaho, University of Illinois, University of Kentucky, University of Louisville, University of Michigan, University of Minnesota, University of North Dakota, University of Pittsburgh, University of South Carolina, University of Southern California, University of Texas, University of Wyoming, Worchester Polytechnic Institute, West Virginia University.

Not for Profit and Independent Associations: American Chemistry Council, American Chemical Society, Agenda 2020, Clean Energy Smart Manufacturing Institute, Digital Manufacturing and Design Innovation Institute, Gas Technology Institute, Glass Manufacturers Industry Council, Institute for Advanced Composites Manufacturing Innovation, National Society of Black Engineers, Research Triangle Institute, Society of Chemical Manufacturing and Affiliates, Southern Research Institute.

Laboratories: The Ames Laboratory, Idaho National Laboratory, Lawrence Livermore National Laboratory, National Energy Technology Laboratory, Oak Ridge National Laboratory, Pacific Northwest National Laboratory, Savannah River National Laboratory, The Forest Products Laboratory (U.S. Forest Service), The National Risk Management Laboratory (EPA).

Ongoing Institute Competitions

In addition to the three institutes announced since December 9, other Manufacturing USA institute topics are now under competition in the areas of:

•      Sustainable materials manufacturing. In collaboration with the Department of Energy, the winner of the competition for the Reducing Embodied Energy and Decreasing Emissions (REMADE) in Materials Manufacturing Institute will focus on reducing the total lifetime use of energy in manufactured materials by developing new cradle-to-cradle technologies for the reuse, recycling, and remanufacturing of manmade materials. U.S. manufacturing consumes nearly a third of the nation's total energy use annually, with much of that energy embodied in the physical products made in manufacturing. New technologies to better repurpose these materials could save U.S. manufacturers and the nation up to 1.6 quadrillion BTU of energy annually, equivalent to 280 million barrels of oil, or a month's worth of domestic oil imports. Read more here.

•      Collaborative robotics. Together with the Department of Defense, the winner of the competition for the Robots in Manufacturing Environments Manufacturing USA Institute will focus on building U.S. leadership in smart collaborative robotics, where advanced robots work alongside humans seamlessly, safely, and intuitively to do the heavy lifting on an assembly line or handleintricate or dangerous tasks with precision. People collaborating with robots has the potential to change a broad swath of manufacturing sectors, from defense and space to automotive and health, enabling the reliable and efficient production of high-quality, customized products. Read more here.

•      Industry-proposed topic. Leveraging authorities from the Revitalizing American Manufacturing and Innovation Act with broad bipartisan support in Congress, the Department of Commerce has launched the first "open topic" institute competition. This competition is open to any topic proposed by industry not already addressed by a manufacturing innovation institute. In addition to NIIMBL, which is awarded using FY2016 funds, additional institutes may be awarded from this competition, subject to the availability of additional funds. The open topic competition design allows industry to propose technology areas seen as critical by leading manufacturers to the competitiveness of U.S. manufacturing. Read more here.

Early Successes from Manufacturing USA

Together, the Manufacturing USA institutes are already enhancing U.S. competitiveness in advanced manufacturing—from helping Youngstown, OH attract over $90 million in new manufacturing investments to its region and train 14,000 workers in the fundamentals of 3D printing for businesses, to supporting companies like X-FAB in Lubbock, TX upgrade to next-generation power semiconductors and sustain hundreds of jobs. These public-private partnerships are bringing value to their members and regions by providing:

•      Technological Innovation: By accelerating the transition from design to Made in USA, the institutes are developing emerging manufacturing technologies—for example, America Makes, the National Additive Manufacturing Innovation Institute in Youngstown, OH enabled one of its founding members, Oxford Performance Materials, Inc., to become the first company to receive clearance from the U.S. Food & Drug Administration to manufacture 3D-printed polymer implants for use in surgical procedures in the United States.

•      Collaborative Constituencies: The institutes align pre-competitive industry priorities by combining the efforts of manufacturers across geographies and supply chains—for example, the American Institute for Manufacturing Integrated Photonics (AIM Photonics), the Integrated Photonics Institute in Rochester, NY, has members on both coasts that, collectively, comprise the entire supply chain for integrated photonics, from microfabrication processing training and circuit design centers in Massachusetts; to wafer foundry, packaging, and assembly centers in New York; to integrated photonic device manufacturers in California.

•      Leveraged Investments: For companies, institute membership provides access to unique equipment and capabilities that are too costly for any one company to undertake—for example, Advanced Functional Fabrics of America (AFFOA), the Revolutionary Fibers and Textiles institute in Cambridge, MA, is standing up a distributed, on-demand foundry to rapidly identify domestic manufacturing pathways within its membership to accelerate the design-to-product process.

•      Networked Expertise: Manufacturing USA is at its best when the institutes are working together— for example, to create a talent pipeline of multi-skilled manufacturing technicians. This cross-institute effort is designed to match talent demands from industry members with the best content from academia members, define promising career pathways, and align workforce investment resources across municipalities, states, and regions.

•      Customized Training: Institutes act as "teaching factories," providing hands-on factory workforce training for the relevant technology-- for example, NC State, the lead for Power America, has created a Master's of Science concentration focused on wide band gap semiconductor power electronics. More than 200 graduate students at NC State and member universities of Power America are now studying power electronics each year. As a result, over 225 freshman engineering students have been introduced to wide band gap semiconductors, building a talent pipeline of future graduates.

•      Business Opportunities: By developing national expertise across their supply chains, the institutes are creating new reasons for companies to locate jobs and investment in their regions and the United States—for example, Leisure Pools, a polymer composite pool manufacturer originally from Australia, has relocated its facilities to be near the Institute for Advanced Composites Manufacturing Innovation (IACMI) in Knoxville, TN, as Leisure Pool moves into new areas to become an advanced manufacturer of carbon fiber composite material products and adds up to 1,000 jobs in Knoxville over the next decade.

•      Innovation Ecosystems: The institutes are creating trusted environments, knitting together technical expertise across supply chains to craft new business opportunities—for example, the Digital Manufacturing and Design Innovation Institute (DMDII) in Chicago, IL is providing space within its facilities for start-ups developing their business, facilitating relationships between young companies and large industrial members through collaborative projects.

•      Rejuvenated Neighborhoods: By anchoring regional manufacturing competitiveness, the institutes are breathing new life into the manufacturing regions where they are located—for example, Lightweight Innovations for Tomorrow (LIFT), the lightweight and modern metals manufacturing institute in Detroit, MI, has transformed a former factory that was abandoned during the wave of offshoring in the early 2000s, rejuvenating one of Detroit's oldest neighborhoods.

To learn more about the open competitions for these next manufacturing innovation institutes, please visit Manufacturing.gov. In addition to today's announcement, the established manufacturing innovation institutes are:

•      America Makes, the National Additive Manufacturing Innovation Institute (Youngstown, OH)

•      Digital Manufacturing and Design Innovation Institute (Chicago, IL)

•      Lightweight Innovations for Tomorrow (Detroit, MI)

•      Power America (Raleigh, NC)

•      Institute for Advanced Composites Manufacturing Innovation (Knoxville, TN)

•      American Institute for Manufacturing Integrated Photonics (Rochester, NY)

•      Next Flex, the Flexible Hybrid Electronics Manufacturing Innovation Institute (San Jose, CA)

•      Advanced Functional Fabrics of America (Cambridge, MA)

•      Smart Manufacturing Innovation Institute (Los Angeles, CA)

•      Rapid Advancement in Process Intensification Deployment (New York, NY)

•      National Institute for Innovation in Manufacturing Biopharmaceuticals (Newark, DE)

Barack Obama, Fact Sheet: Obama Administration Announces New Manufacturing USA Institute, Third Institute Awarded in Three Weeks Online by Gerhard Peters and John T. Woolley, The American Presidency Project https://www.presidency.ucsb.edu/node/322605

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